Mass Spectrometry Instrumentation

Q Exactive HFX with Waters H-class Acquity

HIGH RESOLUTION

ThermoScientific Q Exactive HF-X

Equipped with Waters Acquity H-class UPLC
Mass Range: 50 to 4,000 Da
Resolution: 100, 000 at m/z 400 at 1Hz, >750,000 at m/z 400 at slower scan repetition rates
Mass Accuracy Capabilities: < 1.2 ppm RMS error with external calibration, < 1 ppm RMS error with internal calibration
Sensitivity: Attomole range for peptides
MS, MS/MS and MSn analysis
ECD capabilities
Best suited for: Molecular formula confirmation, accurate mass, structure elucidation

ThermoScientific Exactive GC

Equipped with Autosampler
Mass Range: 30 to 700 Da
Resolution: up to 50,000 at m/z 272
Mass Accuracy Capabilities: < 3.0 ppm RMS error with external calibration, < 1 ppm RMS error with internal calibration
EI and CI capabilities
Best suited for: Volatile compound speciation/separation, molecular formula confirmation, accurate mass, structure elucidation

Agilent 6220 TOF

Equipped with Agilent 1200 HPLC system
Mass Range: 150 to 3200 Da
Resolution: < 20,000
Mass Accuracy Capabilities: 1-5 ppm
Best suited for:  molecular formula confirmation, accurate mass

 

LOW RESOLUTION

Thermo TSQ Vantage Ultra – Triple Quad

Equipped with Waters Acquity Class UPLC system
Mass Range: 30-3000 Da
MS and MS/MS analysis
Best suited for: Quantitation and sample screening

Finnigan LTQ – Ion Trap

Equipped with Surveyor HPLC system
Mass Range: 30-2000 Da
MS and MSn analysis
Best suited for: Sample Screening